Avian Tuberculosis (Mycobacterium Avium) PDD Syndrome


Various skin test
Various skin test

Mycobacterium (ATB) – Nonmotile, straight or slightly curved rods measuring 0.2­0.6 x 1.0 m. Rods are Gram positive, while being difficult to stain. Cells that have been stained with basic fuchsin resist decolorization with acidic ethanol and are hence known as acid­alcohol­fast bacilli (AFB). This is owing to the high lipid content of mycobacterial cell walls.

There are seventy­one legitimately recognized Mycobacterium species and three subspecies. The genus’s main pathogens include M. M. bovis M. leprae and M. leprae TB, but thirty­two species are recognized to be harmful to humans or animals in total. Other Mycobacteria species than those listed above are referred to as “atypical mycobacteria.” Among the atypical mycobacteria, Mycobacterium avium complex species are the most usually seen pathogens. The M. The avium complex (MAC) is thought to include M. M. avium M. avium, subspecies paratuberculosis avium subspecies silvaticum, as well as M. intracellulare. Poorly recognized strains that bear some resemblance to M. Avium is commonly and wrongly assigned to the complex. Within the M, there are over 20 identified serotypes. complicated avium

Most birds have proven susceptibility to M., including parrots, parakeets, cranes, sparrows, starlings, emus, waterfowl raptors, and softbills. avium. It is thought that under ideal circumstances, practically all bird species are vulnerable to avian TB. It is especially common in areas with a high population density, such as zoos or bird collections.


M. Avium infections are classified as “open,” which means that affected birds routinely shed substantial quantities of organism into the environment.
M. Avium is spread by the eating and inhalation of pathogenic organisms aerosolized from feces. Birds incubate for weeks to years. The most prevalent way of infection is via the intake of contaminated food and drink. When consumed, the organism spreads throughout the bird’s body and is excreted in vast quantities. If the bacteria is breathed, it may cause pulmonary lesions. Skin invasion is also possible. It is possible for contaminated eggs to spread, although it is uncommon.

The M. transmission Avium transmission from person to human has not been shown satisfactorily, and all infections are considered to be of environmental origin.


A bird with a normal body weight and look might die suddenly in various conditions. However, most birds with tuberculosis will acquire symptoms such as increasing weight loss despite a strong appetite, depression, diarrhea, increased thirst, and respiratory problems. Egg production is often reduced in birds that were producing eggs. It is quite tough to remove the illness once it has appeared. The most common consequence is death.

Birds with the intestinal type often present with chronic wasting illness, with Proventricular Dilatation Syndrome frequently being one of the probable disorders. Depression, diarrhea, excessive urination (polyuria), abdominal distention, lameness, and difficulties breathing may accompany weight loss.


Avoiding M. Minimize stress and overcrowding; provide sufficient ventilation; and prevent malnutrition with a nutritious food. Taking command of an M. In zoos, bird gardens, and private aviaries, avium outbreaks may be extremely difficult to eliminate. New aviary arrivals should be isolated for at least 1-2 months. M’s new additions are being tested. Avium is also useful in preventing epidemics.


All M. Avium isolates studied to date are completely resistant to antituberculous medications presently used in people. ATB is exceedingly difficult to cure, and in many instances, therapy is not regarded a feasible option.


Culture of the M is a complex and time-consuming procedure. Avium organism in the laboratory There may be an increased white blood cell count as well as a decreased red blood cell count. Staining methods may occasionally be used to detect germs in feces. This is not unique since other acid-fast bacteria that are not M. Avium may be present as well. ABI employs two methods for evaluating M. avium. PCR methods that identify the actual pathogen and ELISA assays that detect specific antibodies for M. avium. PCR tests are thought to be the most sensitive and quickest approach for identifying M. avium, while ELISA tests aid in identifying M. avium.


Biopsies of the liver, intestinal system, spleen, and lungs were performed postmortem. Is one of the most effective methods of diagnosing the condition. Whole blood, serum, vent, and throat swabs may all be utilized for general screening. It is preferable to send blood and swab samples for testing.


Prior to delivery, samples should be kept at 4 degrees Celsius. Overnight shipping of samples in a transport medium or as a dry swab is required.

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